However, at reasonable dosages and using Proviron® most of them and cabergoline can be avoided. Strictly necessary for the post-cycle therapy with the drug Clomid or Nolvadex. Pharmabol 10. PharmaBOL 10, also known as Dianabol - is an oral anabolic steroid, shown in the line Pharmacom Labs Inc.
It stimulates anabolic processes and inhibits catabolic, improves digestion of protein and calcium. It leads to a decrease in fat deposits and a positive nitrogen balance. PharmaBOL 10 has a strongly pronounced anabolic and androgenic properties, because there was a rapid increase in strength and muscle mass builder, this increase is the hypertrophy of muscle fibers, which occurs due to enhanced water retention in organizme.Pri use PharmaBOL 10 each athlete will be able to get the result 1-2 kg of muscle per week for one month, with appropriate nutrition and proper training. Dosages PharmaBOL 10 different for each athlete.
For example, beginners best used PharmaBOL 10, at a dose 30-40mg per day, and people with experience from the use of 50 mg or more per day, depending on their goals and objectives, and is usually combined PharmaNAN (Nandrolone Dekonat) or PharmaNAN P 100 (Nandrolone Phenylpropionate) .Pobochnye PharmaBOL effects at a dose of 10 to 30mg virtually absent, but there may be at a very large number of long-term use of the drug, and this is reflected in the fact that Dianabol has little burden on the liver, greatly exaggerated by public opinion. Also, slight increases in blood pressure and increased heart rate, due to the increased water content in the body may also occur acne on the face, back, arms, chest, due to increased skin oiliness. All side effects are absolutely after receiving PharmaBOL 10. Post-cycle therapy for the drug, taking into account that the course lasts no more than 80 days do not actually need.
Pharmasib 15. PHARMASIB tab 15 50 Mode of action - anorectic. It inhibits the reuptake of neurotransmitters - serotonin and norepinephrine in the synaptic cleft, potentiates the synergistic interaction of the central noradrenalin- and serotonergic systems. Reduces appetite and food intake (increases the feeling of fullness), increases thermogenesis (due to the activation mediated by beta3-adrenoceptor), affects the brown adipose tissue.
Formed in the body active metabolites (primary and secondary amines), sibutramine significantly superior in their ability to inhibit the reuptake of serotonin and noradrenaline. In in vitro studies also active metabolites block the reuptake of dopamine, but 3-fold weaker than that of 5-HT and noradrenaline. Neither sibutramine or active metabolites do not affect the release of monoamines and MAO activity do not interact with neurotransmitter receptors, including serotonergic, adrenergic, dopaminergic, benzodiazepine and glutamate (NMDA), no anticholinergic and antihistaminic actions. It inhibits capture of 5-HT and platelet function may change trombotsitov.Snizhenie body weight accompanied by increased serum concentrations of HDL cholesterol and lowering of triglyceride, total cholesterol, LDL cholesterol and uric acid.
During treatment, there is a slight rise in blood pressure at rest (1-3 mm Hg) and a moderate increase in pulse rate (3-7 beats. / Min), but in rare cases may be more pronounced changes. In an application with inhibitors of microsomal oxidation increases in heart rate (2.5 beats. / Min) and lengthens the interval QT (9.5 ms) .In 2-year studies in rats and mice at doses, as a result of which the observed total area under the concentration - time (AUCs) for two active metabolites exceeded those achieved by MRDC in 0,5-21 times, increases the incidence of benign testicular interstitial tissue predominantly in male rats.
Carcinogenic effects in mice and female rats were found. Not mutagenic action does not affect fertility. When administered to rats doses, AUCs both active metabolite which is 43 times higher than observed in the employment MRDC, teratogenic effects have been detected. However, in studies conducted in rabbits line Dutch Belted under conditions when AUCs active metabolites of sibutramine was 5 times greater than using MRDC, in the offspring were observed anomaly physical development (change in shape or size of the muzzle, ear, tail, the thickness of bones ).
[source not specified 61 days] After oral administration, rapidly absorbed from the gastrointestinal tract is not less than 77%. In the first pass through the liver biotransformation under the influence of CYP3A4 cytochrome P450 with the formation of two active metabolites (mono and didesmetilsibutramin). After administration of a single dose of 15 mg monodesmetilsibutramina Cmax is 4 ng / mL (3.2-4.8 ng / ml) didesmetilsibutramina - 6.4 ng / ml (5,6-7,2 ng / ml). Cmax achieved through 1.2 hours (sibutramine), 3-4 hours (active metabolites).
Simultaneous food intake lowers Cmax of metabolites by 30% and increases time to achieve 3 hours without changing the AUC. Rapidly distributed to tissues. Protein binding is 97% (sibutramine) and 94% (mono- and didesmetilsibutramin). The equilibrium concentration of the active metabolite in the blood is reached within 4 days after the initiation of treatment, and about 2 times higher than the plasma levels after administration of a single dose.
T1 / 2 sibutramine - 1.1 hours monodesmetilsibutramina - 14 hours didesmetilsibutramina - 16 hours. Active metabolites are hydroxylation and conjugation with formation of inactive metabolites are excreted mainly by the kidneys. Pharmaprov 50. PharmaPROV 50 20 tab - aka Proviron (Mesterolone) is an oral synthetic drug submitted in line Pharmacom Labs Inc (Pharmacom.Labs).
PharmaPROV has no anabolic properties, the main effect of this drug - it prevents the conversion of steroids to estrogen in the body. PharmaPROV prevent gynecomastia, water retention, fat deposition on the female type and other estrogenic side effects. Also raises a reduced sexual interest and potency during or as termination of the steroid course. PharmaPROV often used during preparation for a competition when the particular needs low levels of estrogen and high levels of androgen, as it increases the hardness of the muscles and gives it relief and contoured.
The standard daily dosage for athletes - 50 mg per day, divided into two equal reception. The dosage to 100 mg per day is considered acceptable. Higher doses may result in receiving the opposite effect ozhidaemym.PharmaPROV well tolerated, and side effects at a dose not exceeding 100 mg per day is usually absent. However, sometimes excessive levels of androgens may increase because of what may occur effects such as oily skin, acne, hair growth on the face and body, worsening of baldness.
After stopping PharmaPROV side effects are absolutely. Nandrobol 250 NANDROBOL-250 10ml Nandrobol 250 - N is a long-acting drug, which is characterized by a mild androgenic and high anabolic effect. Active ingredient Nandrobola-250 (Nandrobol 250) is a mixture of esters (a mixture of esters of nandrolone propionate 50mg, nandrolone phenylpropionate 50mg, 50mg nandrolone cypionate, nandrolone decanoate 100mg), which are beginning to act consistently, the result for a long time provided the necessary concentration of the substance. The first takes effect nandrolone propionate (50mg), it prevents the excretion of the drug, due to which the presence of elevated concentrations of the active substance takes 2-3 days.